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. 1972 Jul;111(1):152-5.
doi: 10.1128/jb.111.1.152-155.1972.

Nature of the elimination of the penicillinase plasmid from Staphylococcus aureus by surface-active agents

S A Sonstein, J N Baldwin

Nature of the elimination of the penicillinase plasmid from Staphylococcus aureus by surface-active agents

S A Sonstein et al. J Bacteriol. 1972 Jul.

Abstract

Growth of Stapylococcus aureus in various ionic surface-active agents resulted in loss of the ability to produce penicillinase, whereas growth in nonionic surface-active agents had no effect on penicillinase production. The curing effect of various alkyl sulfates was found to be dependent upon the chain length. Curing by surface-active agents could be inhibited by magnesium. Reciprocal transduction experiments showed that curing by a surface-active agent was a property of the plasmid, not of the bacterial strain in which the plasmic resides.

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References

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