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. 1979 Nov 30;206(1162):53-83.
doi: 10.1098/rspb.1979.0091.

The behaviour of transporting epithelial cells. I. Computer analysis of a basic model

The behaviour of transporting epithelial cells. I. Computer analysis of a basic model

V L Lew et al. Proc R Soc Lond B Biol Sci. .

Abstract

We analyse the non-steady state behaviour of a computer model representing functional epithelial cells. The results show that a simple model of an epithelium, containing the essential ion transport asymmetries of the original Koefoed-Johnsen-Ussing model, predicts much of the observed behaviour of 'tight-type' epithelia under various well characterized experimental conditions.

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