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. 1974 Feb;55(1):78-87.

Studies on a smooth phage-resistant variant of Brucella abortus. I. Immunological properties

M J Corbel, J A Morris

Studies on a smooth phage-resistant variant of Brucella abortus. I. Immunological properties

M J Corbel et al. Br J Exp Pathol. 1974 Feb.

Abstract

The immunological properties of a phage-resistant variant of Brucella abortus were examined. This variant, which was smooth and identical with the phage-susceptible parent strain in all cultural, biochemical and serological properties studied, was strongly antigenic in rabbits and guineapigs, inducing high titres of antibodies and delayed hypersensitivity to Br. abortus antigens. It was also fully virulent for mice and guinea-pigs.

Contrary to other reports on the properties of phage-resistant Brucella strains, the in vivo properties of this strain showed no evidence of attenuation of virulence.

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