Comparison of indirect haemagglutination and immunofluorescence tests for malaria antibody in Aotus monkeys infected with Plasmodium falciparum. Application of indirect haemagglutination tests for malaria

Abstract

Longitudinal observations were made on 6 Aotus monkeys repeatedly infected with Plasmodium falciparum (West African and Palo Alto strains). Immunofluorescence titres were higher than indirect haemagglutination titres in the primary phase of the infections. Both serological tests were consistently positive later in the infections. Precipitins were often not detectable even during episodes of parasitaemia.