doi: 10.1136/bmj.3.5931.608.
Rosette-forming T lymphocytes and cell-mediated immunity in malnutrition
- PMID: 4214461
- PMCID: PMC1611609
- DOI: 10.1136/bmj.3.5931.608
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Rosette-forming T lymphocytes and cell-mediated immunity in malnutrition
Br Med J.
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Abstract
The frequency of rosette-forming thymus-dependent lymphocytes was reduced in the peripheral blood of malnourished infants and children. The reduced frequency parallelled the impairment of delayed hypersensitivity response to 2, 4-dinitrochlorobenzene and decreased DNA synthesis by lymphocytes challenged with phytohaemagglutinin. The abnormalities were reversed on nutritional improvement.
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