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. 1979 Oct 31;65(5):511-6.
doi: 10.1177/030089167906500501.

Standardization of the alkaline elution procedure using X-ray-damaged nuclear DNA

C Bolognesi, C F Cesarone, L Santi

Standardization of the alkaline elution procedure using X-ray-damaged nuclear DNA

C Bolognesi et al. Tumori. .

Abstract

Structural modification of DNA were induced by X-irradiation of crude hepatic nuclei at various dose ranges to standardize DNA damage evaluated by the alkaline elution technique. This quantitative assay can be used as reference for DNA damage induced by the in vivo administration of mutagens and/or carcinogens involved in the environment.

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