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. 1979 Feb 15;35(2):241-2.
doi: 10.1007/BF01920640.

Effect of vitamin A deficiency on rat hepatic and colon epoxide hydrase

Effect of vitamin A deficiency on rat hepatic and colon epoxide hydrase

A A Adekunle et al. Experientia. .

Abstract

Rat liver microsomes and homogenized mucosal linings prepared from vitamin A-supplemented and deficient male rats were used in metabolic studies of 7-3H-styrene oxide. The colon tissue in deficient animals exhibits a significantly higher value of Vmax than the same tissue from vitamin-supplemented animals. The implications of this finding in addition to our earlier observation 10 is discussed in relation to colon carcinoma.

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