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. 1974 Nov;18(3):417-29.

The immunohistological detection of intracellular immunoglobulin in formalin-paraffin sections from multiple myeloma and related conditions using the immunoperoxidase technique

C R Taylor, D Y Mason

The immunohistological detection of intracellular immunoglobulin in formalin-paraffin sections from multiple myeloma and related conditions using the immunoperoxidase technique

C R Taylor et al. Clin Exp Immunol. 1974 Nov.

Abstract

Paraffin sections of tissues from thirty-three cases of plasma cell neoplasia have been examined by an immunoperoxidase method for demonstrating and characterizing intracellular immunoglobulins. The specificity of the method has been confirmed by a comparison of results with the serum paraprotein types analysed independently.

The morphology of some of the immunoglobulin-containing cells is discussed and possible diagnostic applications of the method are briefly described.

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