doi: 10.1126/science.157.3796.1577.
Erythrocyte abnormality in human myopathy
- PMID: 4227064
- DOI: 10.1126/science.157.3796.1577
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Erythrocyte abnormality in human myopathy
Science.
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Abstract
Erythrocyte ghosts isolated from myopathic patients responded to 10(-4) molar ouabain with a dramatic increase in adenosine triphosphatase activity, while identical preparations from normal donors were inhibited by the same drug. These results have been interpreted in terms of a disease-related change in membrane integrity bearing upon function of the transport enzyme.
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