Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1967 Dec 29;158(3809):1694-5.
doi: 10.1126/science.158.3809.1694.

Salicylanilides: a new group of active uncouplers of oxidative phosphorylation

R L Williamson, R L Metcalf

Salicylanilides: a new group of active uncouplers of oxidative phosphorylation

R L Williamson et al. Science. .

Abstract

Investigations using housefly mitochondria revealed several salicylanilide derivatives as the most effective uncoupling agents of oxidative phosphorylation reported so far. Even greater inhibition of the associated P(i)-adenosine triphosphate exchange was shown with these compounds in both housefly and rat-liver mitochondria, and close similarity was observed between the two types of organelles.

PubMed Disclaimer

LinkOut - more resources