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. 1968 Jun;95(6):2177-81.
doi: 10.1128/jb.95.6.2177-2181.1968.

Prevention of staphylococcal bacteriophage activity by antigen A precipitins in human sera

R R Martin, A White

Prevention of staphylococcal bacteriophage activity by antigen A precipitins in human sera

R R Martin et al. J Bacteriol. 1968 Jun.

Abstract

Antigen A precipitins in human sera prevented plaque formation and propagation of staphylococcal bacteriophages. Over 20% of total IgG was removed from human sera by absorption with staphylococci containing antigen A. The specific precipitating antibody in rabbit antisera formed lines of idenity with antigen A precipitins in lower dilutions of human sera but formed lines of nonidenity with antigen A precipitins in higher dilutions of the same sera, suggesting both specific and nonspecific antigen A precipitins in human sera. The specific and nonspecific antigen A precipitins in human sera may prevent the in vivo activity of staphylococcal bacteriophages which have been demonstrated previously in animals whose sera do not contain either specific or nonspecific antigen A precipitins.

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References

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