doi: 10.1038/278227a0.
Structure of the human fetal globin gene locus
- PMID: 423971
- DOI: 10.1038/278227a0
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Structure of the human fetal globin gene locus
Nature.
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Abstract
We have derived a 'map' of restriction enzyme sites in and around the human gamma-globin genes. This has enabled us to show that there are two gamma-globin genes per haploid set, that the genes contain 'introns' within the same regions of DNA as the human beta and delta-globin genes, and that the genes are 3,500 base pairs apart. We conclude that the correct gene organisation of the human beta-like globin locus is GgammaAgammadeltabeta.
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