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. 1969 Sep 5;165(3897):1010-2.
doi: 10.1126/science.165.3897.1010.

Autosomal trisomy in a chimpanzee: resemblance to Down's syndrome

H M McClure, K H Belden, W A Pieper, C B Jacobson

Autosomal trisomy in a chimpanzee: resemblance to Down's syndrome

H M McClure et al. Science. .

Abstract

An infant chimpanzee (Pan troglodytes) with clinical, behavioral, and cytogenetic features similar to those in Down's syndrome is described. The infant shows retarded growth rate, congenital abnormalities, retarded neurologic and postural development, epicanthus, hyperflexibility of the joints, muscle hypotonia, and trisomy of a small acrocentric chromosome.

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