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. 1979 Jan;6(1):259-74.
doi: 10.1093/nar/6.1.259.

Multiacetylated forms of H4 are found in a putative transcriptionally competent chromatin fraction from trout testis

Multiacetylated forms of H4 are found in a putative transcriptionally competent chromatin fraction from trout testis

B Levy-Wilson et al. Nucleic Acids Res. 1979 Jan.

Abstract

We have examined the distribution of acetylated histones derived from various trout testis chromatin fractions of different composition. Our results indicate that a chromatin fraction, preferentially solubilized by micrococcal nuclease, containing the bulk of the HMG proteins and similar to a fraction released from intact trout nuclei and previously shown to be enriched in transcribed DNA sequences also possesses high levels of multiacetylated species of H4. Histones 2A, 2B and 3 are also acetylated in this particular chromatin fraction. Monoacetylated species of the 4 inner nucleosomal histones appear to be characteristic of the nucleohistone portion of trout testis chromatin.

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