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. 1969 Dec 27;4(5686):778-81.
doi: 10.1136/bmj.4.5686.778.

Intraluminal transport of iron from stomach to small-intestinal mucosa

A Jacobs, P M Miles

Intraluminal transport of iron from stomach to small-intestinal mucosa

A Jacobs et al. Br Med J. .

Abstract

Inorganic iron rarely exceeds 10(-4) molar concentration in the stomach after a meal. Natural sugars, ascorbic acid, citric acid, and amino-acids form iron complexes, and if they are present in the meal complexing occurs when the gastric contents are neutralized. In their absence an iron complex is formed with gastric mucopolysaccharide, which acts as a carrier, stable at neutral pH. Iron can be detached from this carrier at neutral pH by some low molecular weight substances, of which citric acid, ascorbic acid, and cysteine are particularly effective at low concentrations. Under normal circumstances most of the iron released from food in the stomach becomes bound to the mucopolysaccharide carrier.

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References

    1. Surg Forum. 1965;16:319-21 - PubMed
    1. Lancet. 1966 Dec 31;2(7479):1431-3 - PubMed
    1. Lancet. 1967 Apr 29;1(7496):926-7 - PubMed
    1. Lancet. 1968 Mar 23;1(7543):614-6 - PubMed
    1. Acta Med Okayama. 1967 Aug;21(4):177-83 - PubMed

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