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. 1971 Jan;121(2):227-33.
doi: 10.1042/bj1210227.

Nature of the interaction of chondroitin 4-sulphate and chondroitin sulphate-proteoglycan with collagen

B Obrink, A Wasteson

Nature of the interaction of chondroitin 4-sulphate and chondroitin sulphate-proteoglycan with collagen

B Obrink et al. Biochem J. 1971 Jan.

Abstract

The electrostatic interaction of chondroitin sulphate and the chondroitin sulphate-proteoglycan with collagen was studied by chromatography of the glycosaminoglycan and the proteoglycan on a collagen gel. The observed binding between the macromolecules increased with decreasing pH and ionic strength, and was significant under physiological conditions. A study of the interaction between chondroitin sulphate and a preparation of soluble collagen, with a partition-equilibrium technique, afforded similar results.

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References

    1. Anal Biochem. 1965 Sep;12(3):547-58 - PubMed
    1. Biochem J. 1965 Sep;96(3):710-6 - PubMed
    1. Biochim Biophys Acta. 1966 Feb 7;112(2):346-62 - PubMed
    1. Biochim Biophys Acta. 1967 Mar 22;136(2):191-8 - PubMed
    1. Biochim Biophys Acta. 1968 Aug 13;160(3):435-46 - PubMed