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. 1972 Jan;69(1):15-9.
doi: 10.1073/pnas.69.1.15.

Adenosine triphosphatase associated with adenosine triphosphate-dependent deoxyribonuclease (recB-recC enzyme-E. coli-ATP to phosphodiester hydrolysis ratio-DNA-dependent ATPase activity)

F G Nobrega, F H Rola, M Pasetto-Nobrega, M Oishi

Adenosine triphosphatase associated with adenosine triphosphate-dependent deoxyribonuclease (recB-recC enzyme-E. coli-ATP to phosphodiester hydrolysis ratio-DNA-dependent ATPase activity)

F G Nobrega et al. Proc Natl Acad Sci U S A. 1972 Jan.

Abstract

An ATPase activity that is completely dependent on DNA is associated with the ATP-dependent DNase (recB-recC enzyme) purified from Escherichia coli. There is a strong correlation between the ATPase and the DNase activities under various assay conditions. With E. coli DNA as substrate, 8-9 molecules of ATP are hydrolyzed to ADP and inorganic phosphate for every phosphodiester bond hydrolyzed by the DNase. The possible functional relationship of the ATPase and DNase activities is discussed.

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References

    1. Proc Natl Acad Sci U S A. 1970 Apr;65(4):955-61 - PubMed
    1. Proc Natl Acad Sci U S A. 1969 Dec;64(4):1292-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1970 Sep;67(1):434-41 - PubMed
    1. J Mol Biol. 1961 Feb;3:47-60 - PubMed
    1. Biochem J. 1964 Jan;90(1):147-9 - PubMed

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