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Case Reports
. 1979 Feb;115(2):201-2.

Generalized malignant acanthosis nigricans

G R Mikhail, D M Fachnie, B H Drukker, R Farah, H M Allen
  • PMID: 426529
Case Reports

Generalized malignant acanthosis nigricans

G R Mikhail et al. Arch Dermatol. 1979 Feb.

Abstract

We report a case of generalized malignant acanthosis nigricans (AN) secondary to metastasizing squamous cell carcinoma of the cervix uteri. The disease initially manifested in the perineum as condyloma acuminatum-like lesions. Subsequently, most of the cutaneous surface and the mucosa of the vulva, mouth, tongue, and the palpebral conjunctiva became involved. The association of AN with a squamous cell carcinoma is rare, and conjunctival involvement is unusual.

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