[Chronic gastritis and cancer of the stomach]

Abstract

The paper analyses interrelationships between chronic gastritis and carcinoma of the stomach. It has been recognized that various forms of chronic gastritis preceed carcinoma of the stomach. The source of the carcinoma origin is the epithelium of the gastric pit, intestinal and mixed epithelium. The nearest precursors of the carcinoma are foci of dysplasia of the epithelium developing in pits, intestinal cryptae and mixed glands. Proceeding from the regular emergence of the stomach carcinoma against the background of chromic gastritis, features of carcinogenesis in the stomach, and morphogenesis of chronic gastritis, the authors substantiate the pathogenetic connection between chronic gastritis and carcinoma of the stomach. Secondary changes in the gastric system have been found to develop in the III--IV stages of carcinoma. The main morphological features of carcinoma of the stomach of different histogenesis are characterized.