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. 1973 Sep 14;181(4104):1057-8.
doi: 10.1126/science.181.4104.1057.

Breast cancer: induction of differentiation by embryonic tissue

J J DeCosse, C L Gossens, J F Kuzma, B R Unsworth

Breast cancer: induction of differentiation by embryonic tissue

J J DeCosse et al. Science. .

Abstract

A mouse mammary tumor, adenocarcinoma BW 10232, was maintained in vitro for 14 days, separated from embryonic mammary mesenchyme by a Millipore filter. Tubules developed in the tumor; deoxyibonucleic acid synthisis declined; and a presumptive acid mucopolysaccharide matrix, not evident in the controls, appeared.

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