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. 1973 Oct;54(5):555-65.

Enzyme changes in experimental renal microcystic disease

Enzyme changes in experimental renal microcystic disease

J E McGeoch et al. Br J Exp Pathol. 1973 Oct.

Abstract

In an experimental model of human microcystic disease in rats, abnormal changes in tubular enzyme activity were detected as the lesion developed. Decreased activity for alkaline phosphatase, Mg++-ATPase, and Na+K+-ATPase were detected mainly in the proximal tubule, where the lesion was most pronounced. Areas of early fibrosis between the cystic tubules were associated with acid phosphatase activity.

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References

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