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Comparative Study
. 1974 Jan 19;110(2):173 passim.

Treatment of gonorrheal urethritis with spectinomycin hydrochloride

J Brown, O Tabert, J D Hanna, P L Rentiers
Comparative Study

Treatment of gonorrheal urethritis with spectinomycin hydrochloride

J Brown et al. Can Med Assoc J. .

Abstract

One hundred and eighty-seven males with uncomplicated gonorrheal urethritis were treated with spectinomycin hydrochloride in a dosage of 2 g. given intramuscularly. A failure rate of 3.2% was observed and no complications of therapy were encountered. In addition, 310 strains of N. gonorrhoeae were tested for susceptibility to penicillin G and spectinomycin. All strains were sensitive to 20 mug./ml. of spectinomycin and this susceptibility appeared to decrease as penicillin resistance increased. A greater incidence of relative resistance to penicillin G was observed than in similar studies from other Canadian areas.

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References

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