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. 1973 Dec;135(4):905-8.
doi: 10.1042/bj1350905.

Binding of oligosaccharides of hyaluronic acid to proteoglycans

T E Hardingham, H Muir

Binding of oligosaccharides of hyaluronic acid to proteoglycans

T E Hardingham et al. Biochem J. 1973 Dec.

Abstract

Oligosaccharides derived from hyaluronic acid were shown to inhibit proteoglycan-hyaluronic acid interaction, as measured in a viscometer. The relative inhibition increased with the size of the oligosaccharide and the results suggested that decasaccharides were the smallest fragments able to bind strongly to the proteoglycan.

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References

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