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. 1974 May;17(1):159-67.

Inter-mouse strain differences in macrophage function and its relationship to antibody responses

J H Passwell, M W Steward, J F Soothill

Inter-mouse strain differences in macrophage function and its relationship to antibody responses

J H Passwell et al. Clin Exp Immunol. 1974 May.

Abstract

Macrohage function, as measured by carbon clearance, differs in different inbred strains. Low affinity (KR) antibody response to HST is associated either with poor carbon clearance, or slow recovery from carbon blockade by macrophages.

Carbon blockade reduces KR, but not Abt in mice with high carbon clearance and KR.

Stilboestrol increases carbon clearance and KR in mice with slow clearance and low KR.

The significance of these findings in pathogenesis and treatment of chronic soluble complex disease is discussed.

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References

    1. Immunology. 1972 Dec;23(6):881-7 - PubMed
    1. J Immunol. 1969 Jul;103(1):71-8 - PubMed
    1. Br J Exp Pathol. 1973 Apr;54(2):198-202 - PubMed
    1. Bacteriol Rev. 1964 Mar;28:30-71 - PubMed
    1. Br Med J. 1963 Jul 6;2(5348):27-31 - PubMed

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