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. 1965 Nov;90(5):1448-54.
doi: 10.1128/jb.90.5.1448-1454.1965.

Detection of viruslike particles in germ-free mice

M Kajima, M Pollard

Detection of viruslike particles in germ-free mice

M Kajima et al. J Bacteriol. 1965 Nov.

Abstract

Kajima, Masahiro (University of Notre Dame, Notre Dame, Ind.), and Morris Pollard. Detection of viruslike particles in germ-free mice. J. Bacteriol. 90:1448-1454. 1965.-Viruslike particles similar in structure to the mouse leukemia agent were detected by electron microscopy in thymus tissues of germ-free AK mice which had developed spontaneous leukemia. In addition, unique viruslike particles (type B) were detected in tissues from spontaneous mammary adenocarcinoma of germ-free C3H mice. Leukemia virus-like particles were also observed in the thymuses of the control AK mice and of the C3H control mice as well as of those with mammary tumors. Germ-free mice are not virus-free. The routes of transmission of leukemia as well as of mammary tumor viruses may be "vertical," through the embryo or placenta.

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References

    1. Proc Soc Exp Biol Med. 1961 Dec;108:715-23 - PubMed
    1. J Biophys Biochem Cytol. 1961 Feb;9:409-14 - PubMed
    1. Cancer Res. 1963 Oct;23:1604-7 - PubMed
    1. J Exp Med. 1964 Nov 1;120:857-68 - PubMed
    1. Cancer Res. 1958 Jun;18(5):491-509 - PubMed

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