doi: 10.1126/science.153.3740.1122.
Heat-labile serum factor required for immunofluorescence of polyoma tumor antigens
- PMID: 4288238
- DOI: 10.1126/science.153.3740.1122
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Heat-labile serum factor required for immunofluorescence of polyoma tumor antigens
Science.
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Abstract
The immunofluorescent demonstration of polyoma tumor antigens in tumor cells requires a heatlabile serum component. With unheated hamster tumor serum, specific fluorescence was observed in polyoma-transformed hamster, mouse, and rat tumor cells. Heated serum usually gave little or no reactivity; the activity of such heated serum could be restored simply by the addition of fresh normal unheated hamster serum.
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