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. 1966 Oct;101(1):120-6.
doi: 10.1042/bj1010120.

Some observations on the periodate oxidation of amino compounds

J R Clamp, L Hough

Some observations on the periodate oxidation of amino compounds

J R Clamp et al. Biochem J. 1966 Oct.

Abstract

Various aliphatic and aromatic amines are oxidized by sodium metaperiodate and these reactions have been studied quantitatively in acidic, unbuffered and basic media. Significant differences have been observed between the behaviour of aliphatic and aromatic amines. Certain compounds also behaved differently under acidic and basic conditions. These reactions are related to the periodate oxidation of amino acids and, from observations on a number of glycine derivatives, a reaction mechanism is proposed for this process.

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References

    1. Biochem J. 1965 Jan;94:17-24 - PubMed