Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1967 Nov;94(5):1509-15.
doi: 10.1128/jb.94.5.1509-1515.1967.

Effect of some proteins on the yeast cell membrane

D A Yphantis, J L Dainko, F Schlenk

Effect of some proteins on the yeast cell membrane

D A Yphantis et al. J Bacteriol. 1967 Nov.

Abstract

Yeast cells, Candida utilis, in water suspension and in the absence of electrolytes were found to be very sensitive to several proteins of moderate size, including ribonuclease, protamine, lysozyme, bovine serum albumin, cytochrome c, and myoglobin. Viability ceases rapidly, and ultraviolet-absorbing compounds (260 mmu) and the amino acid pool are released into the medium. The ultraviolet-absorbing material appears to be the nucleotide and coenzyme fraction usually extracted by 0.2 n perchloric acid at low temperature. The ribonucleic acid fraction remains in the cell ghosts and can be released by ribonuclease. The enzymatic properties of some of these proteins have no relation to their damaging effect on the cell membrane. Poly-l-lysine shows the same activity.

PubMed Disclaimer

References

    1. J Bacteriol. 1966 Feb;91(2):673-6 - PubMed
    1. Arch Biochem Biophys. 1966 Jan;113(1):127-33 - PubMed
    1. Biochim Biophys Acta. 1956 Jul;21(1):18-23 - PubMed
    1. J Bacteriol. 1964 Apr;87:945-51 - PubMed
    1. Adv Protein Chem. 1959;14:391-478 - PubMed

MeSH terms

LinkOut - more resources