A seasonal variation study of 25-hydroxyvitamin D3 serum levels in normal humans
- PMID: 429522
- DOI: 10.1210/jcem-48-5-771
A seasonal variation study of 25-hydroxyvitamin D3 serum levels in normal humans
Abstract
A population residing in the approximate area of Kalamazoo, MI (latitude north, 42 degrees 17' 29''; longitude west 85 degrees 35' 14''), was examined to determine the influence of seasonal variation on human 25-hydroxyvitamin D3 serum levels. Males and females, ranging in age from 16--64 yr of age and judged normal based on laboratory evaluation and physical examination, participated in the 12-month study. Measurement of 25-hydroxyvitamin D3 serum levels was made by high performance liquid chromatography. A correlation coefficient of 0.776 (P = 0.003) was obtained by comparing average monthly 25-hydroxyvitamin D3 serum levels to average monthly temperatures. A comparison of approximated monthly amounts of sunlight to average monthly 25-hydroxyvitamin D3 serum levels produced a correlation coefficient of 0.747 (p = 0.005). In addition, changes in 25-hydroxyvitamin D3 levels for the population examined fitted a model that demonstrated a relationship to sex and a highly significant periodic relationship to time.
Similar articles
-
Serum 25-hydroxyvitamin D levels in normal subjects: seasonal variations and relationships with parathyroid hormone and osteocalcin.J Nucl Biol Med (1991). 1993 Jun;37(2):77-82. J Nucl Biol Med (1991). 1993. PMID: 8373837
-
A seasonal difference in serum 25-hydroxyvitamin D3 in a Finnish population.Med Biol. 1980 Feb;58(1):49-52. Med Biol. 1980. PMID: 7382580
-
Absence of seasonal variation in serum concentrations of 1,25-dihydroxyvitamin D despite a rise in 25-hydroxyvitamin D in summer.J Clin Endocrinol Metab. 1981 Jul;53(1):139-42. doi: 10.1210/jcem-53-1-139. J Clin Endocrinol Metab. 1981. PMID: 6972382
-
[Serum levels of 25-hydroxyvitamin D in the normal population of Buenos Aires: its seasonal variation].Medicina (B Aires). 1987;47(3):268-72. Medicina (B Aires). 1987. PMID: 3441206 Spanish. No abstract available.
-
The seasonality of slipped upper femoral epiphysis--meta-analysis: a possible association with vitamin D.Hip Int. 2015 Nov-Dec;25(6):495-501. doi: 10.5301/hipint.5000203. Epub 2015 May 29. Hip Int. 2015. PMID: 26044532 Review.
Cited by
-
Seasonal variation in bone metabolism in young healthy subjects.Calcif Tissue Int. 1991 Aug;49(2):84-9. doi: 10.1007/BF02565126. Calcif Tissue Int. 1991. PMID: 1655177 Clinical Trial.
-
Seasonal variation in children with developmental dysplasia of the hip.J Child Orthop. 2014 Feb;8(1):11-22. doi: 10.1007/s11832-014-0558-3. Epub 2014 Feb 6. J Child Orthop. 2014. PMID: 24500336 Free PMC article.
-
Seasonal changes in lead absorption in laboratory rats.Environ Health Perspect. 1987 Aug;73:209-14. doi: 10.1289/ehp.8773209. Environ Health Perspect. 1987. PMID: 3665864 Free PMC article.
-
Effect of aging on vitamin D stores and bone density in women.Calcif Tissue Int. 1987 May;40(5):241-3. doi: 10.1007/BF02555255. Calcif Tissue Int. 1987. PMID: 3107776
-
Genes mediating environment interactions in type 1 diabetes.Rev Diabet Stud. 2005 Winter;2(4):192-207. doi: 10.1900/RDS.2005.2.192. Epub 2006 Feb 10. Rev Diabet Stud. 2005. PMID: 17491695 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
