Behavioral and electrophysiological effects of unilateral optic tract section in ordinary and Siamese cats

Abstract

In ordinary cats, section of one optic tract produced a complete contralateral hemianopsia in both eyes. Single-unit recordings showed a normal representation of the contralateral nasal retina and ipsilateral temporal retina in the SC on the side of the intact optic tract. In addition, in the rostral portion of this SC there was a representation of a small portion of the contralateral temporal retina. This portion was apposed to the vertical meridian and its width was at most 6 degrees. In the anterior half of the SC on the side of the optic tract section, despite the interruption of any direct optic input, there was an extensive representation of the ipsilateral nasal retina and the contralateral temporal retina. This indirect visual input to the SC ipsilateral to the optic tract section was absent in a cat with a section of the forebrain commissures. In Boston Siamese cats, section of one optic tract led to a virtually complete blindness in the eye contralateral to the section, whereas the other eye retained a full visual field, although the responsiveness of the temporal retina beyond 20 degrees from the vertical meridian was reduced. Similarly, the nasal hemiretina and most of the temporal hemiretina on the side of the section were represented in the opposite SC, whereas stimulation of the eye contralateral to the section could not drive SC units. There was some evidence that the visual field of the eye on the side of the section could at least in part be represented in the SC on the same side. The findings indicate that the crossed projections from temporal hemiretina in the ordinary cat, and the uncrossed projections from temporal hemiretina in the Siamese cat are insufficient by themselves to sustain visual orientation and to drive SC neurons. Each half of the visual field in the ordinary cat, and the field of each eye in the Siamese cat, can be represented in the ipsilateral SC via across-the-midline, indirect connections.