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. 1979 Apr;82(2):309-17.
doi: 10.1017/s0022172400025729.

An inherited mild middle-aged adiposity in wild mice

M E Wallace, F M MacSwiney

An inherited mild middle-aged adiposity in wild mice

M E Wallace et al. J Hyg (Lond). 1979 Apr.

Abstract

In a warfarin-resistant population of wild mice reared in the laboratory, a dominant gene for adiposity, Ad, was found to segregate. The onset of obesity is at 4--6 months, and adipose mice suffer from hyperinsulinaemia; the sexes differ in penetrance, males having greater penetrance then females. Linkage backcrosses show the gene to be situated on chromosome 7 with about 25% recombination with the closely linked warfarin-resistance genes War, and frizzy, fr. The finding of adipose in two other wild populations also carrying War is discussed as an ecological and physiological problem.

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References

    1. Lancet. 1976 Oct 9;2(7989):770-3 - PubMed
    1. J Hyg (Lond). 1978 Feb;80(1):69-75 - PubMed
    1. J Hyg (Lond). 1976 Apr;76(2):173-81 - PubMed
    1. Diabetologia. 1973 Aug;9(4):287-93 - PubMed
    1. Diabetologia. 1973 Aug;9(4):294-8 - PubMed

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