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. 1968 Aug 23;161(3843):804-6.
doi: 10.1126/science.161.3843.804.

Interferon: protection of cells infected with an intracellular protozoan (Toxoplasma gondii)

J S Remington, T C Merigan

Interferon: protection of cells infected with an intracellular protozoan (Toxoplasma gondii)

J S Remington et al. Science. .

Abstract

Chick and mouse cell monolayers treated with interferon were significantly protected from destruction by toxoplasma. The results suggest that fewer numbers of organisms were released from interferon-treated cells. Interferons were uniformly more active in a viral assay than in a toxoplasma assay, and they had the same properties in both assays. The data suggest that interferon activity may be directed against organisms phylogenetically higher than viruses.

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