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. 1968 Oct 4;162(3849):131-2.
doi: 10.1126/science.162.3849.131.

Brain alcohol dehydrogenase

N H Raskin, L Sokoloff

Brain alcohol dehydrogenase

N H Raskin et al. Science. .

Abstract

Significant alcohol dehydrogenase activity has been demonstrated in the soluble fraction of rat brain and is very similar to the liver enzyme in kinetic properties and responses to inhibitors. A cerebral mechanism that oxidizes ethanol may play a significant role in local adjustments during exposure to ethanol and in the pathogenesis of the neural disorders associated with chronic alcohol ingestion or withdrawal.

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