Blood angiotensin II levels of normal and hypertensive subjects
- PMID: 4304429
- PMCID: PMC1982472
- DOI: 10.1136/bmj.1.5647.819
Blood angiotensin II levels of normal and hypertensive subjects
Abstract
A specific radioimmunoassay for angiotensin II has shown that its normal concentration in arterial blood is 2.4+/-1.2 (S.D.) mmug./l00 ml.; the venous level is consistently below this value, being usually 50-75% of it. Definite rises in blood angiotensin II levels were found in some patients with hypertension, both essential and secondary to renal disease. Extremely low levels were observed in two anephric women, and in one patient with Conn's syndrome. This radioimmunoassay offers a valuable alternative to renin bioassay in evaluation of the role of the renal pressor system in clinical disorders associated with hypertension and aldosteronism.
Similar articles
-
Angiotensin II plasma levels in hypertensive patients.Acta Med Scand. 1972 Dec;192(6):507-11. doi: 10.1111/j.0954-6820.1972.tb04855.x. Acta Med Scand. 1972. PMID: 4344949 No abstract available.
-
Specific direct radioimmunoassay of angiotensin II (AT II) in human plasma and the effect of angiotensin converting enzyme (ACE) inhibitor.Immunopharmacology. 1999 Oct 15;44(1-2):199-204. doi: 10.1016/s0162-3109(99)00090-9. Immunopharmacology. 1999. PMID: 10604545
-
Radioimmunoassay of angiotensin and determination of renin activity.Prog Nucl Med. 1972;2:85-106. Prog Nucl Med. 1972. PMID: 4346368 Review. No abstract available.
-
Effect of furosemide administration and upright position on plasma renin activity and angiotensin II in hypertension.Tohoku J Exp Med. 1973 Sep;111(1):71-8. doi: 10.1620/tjem.111.71. Tohoku J Exp Med. 1973. PMID: 4359911 No abstract available.
-
Significance of renin and angiotensin in hypertension.Cardiovasc Clin. 1978;9(1):55-89. Cardiovasc Clin. 1978. PMID: 352522 Review. No abstract available.
Cited by
-
Angiotensin II Attenuates the Bioactivities of Human Endothelial Progenitor Cells via Downregulation of β2-Adrenergic Receptor.Stem Cells Int. 2018 Oct 29;2018:7453161. doi: 10.1155/2018/7453161. eCollection 2018. Stem Cells Int. 2018. PMID: 30510587 Free PMC article.
-
[Determination of plasma renin activity by radioimmunoassay of angiotensin 1. Comparison with bioassay].Klin Wochenschr. 1971 Aug 1;49(15):870-6. doi: 10.1007/BF01513470. Klin Wochenschr. 1971. PMID: 4327894 German. No abstract available.
-
Lack of association between angiotensin-converting enzyme inhibitors and angiotensin receptor blockers and pain improvement in patients with oral cancer.Ecancermedicalscience. 2020 Oct 13;14:1121. doi: 10.3332/ecancer.2020.1121. eCollection 2020. Ecancermedicalscience. 2020. PMID: 33209112 Free PMC article. Review.
-
The RAAS Goodfellas in Cardiovascular System.J Clin Med. 2023 Oct 31;12(21):6873. doi: 10.3390/jcm12216873. J Clin Med. 2023. PMID: 37959338 Free PMC article. Review.
-
Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells.Aging (Albany NY). 2018 Jan 15;10(1):100-114. doi: 10.18632/aging.101362. Aging (Albany NY). 2018. PMID: 29348391 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources