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. 1967 Jun 9;156(3780):1388-92.
doi: 10.1126/science.156.3780.1388.

Force, shortening, and work in muscular contraction: relative contributions to overall energy utilization

Force, shortening, and work in muscular contraction: relative contributions to overall energy utilization

F F Jobsis et al. Science. .

Abstract

The amounts of energy used during muscular contraction under different loads have been compared by measurement of the total amount of disturbance of the concentration of reduced nicotinamide-adenine dinucleotide during the period of oxidative recovery. The results are in quantitative agreement with the concept that three parameters determine the energy utilization: namely the time-integral of the force development, the time-integral of the shortening process, and the mechanical work.

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