doi: 10.1073/pnas.63.2.512.
On the mechanism of action of adrenocorticotropic hormone: the binding of cyclic-3',5'-adenosine monophosphate to an adrenal cortical protein
- PMID: 4308274
- PMCID: PMC223593
- DOI: 10.1073/pnas.63.2.512
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On the mechanism of action of adrenocorticotropic hormone: the binding of cyclic-3',5'-adenosine monophosphate to an adrenal cortical protein
Proc Natl Acad Sci U S A.
1969 Jun.
Abstract
The binding of cyclic 3',5'-adenosine monophosphate (cyclic AMP) within the adrenal cortical cell was studied. Cyclic AMP binds specifically to a protein which is associated predominantly with the microsomal fraction of the cell. The binding protein was purified approximately 100-fold.
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