doi: 10.1126/science.166.3908.1007.
Polyol pathway in aorta: regulation by hormones
- PMID: 4310476
- DOI: 10.1126/science.166.3908.1007
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Polyol pathway in aorta: regulation by hormones
Science.
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Abstract
Aldose reductase is present in human and rabbit aortas and provides a mechanism whereby hyper-glycemia can alter the metabolism of the arterial wall. Aortic sorbitol concentration is regulated by ambient glucose concentration and is increased by epinephrine, isoproterenol, dibutyryl-3',5'-adenosine monophosphate, ouabain, and angiotensin II.
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