doi: 10.1128/JVI.4.5.574-579.1969.
Simian virus 40-induced T and tumor antigens
- PMID: 4311792
- PMCID: PMC375911
- DOI: 10.1128/JVI.4.5.574-579.1969
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Simian virus 40-induced T and tumor antigens
J Virol.
1969 Nov.
Abstract
Antigen extracts from simian virus 40 (SV40) transplanted hamster tumors were studied by rate-zonal centrifugation. Three species or molecular forms of antigen were demonstrated. The major antigen component corresponded to a molecular weight of 65,000 to 75,000, and two larger species were detectable in smaller quantities. Similar studies were carried out on SV40 virus-induced T antigen from BSC-1 cells. Three antigen components were again detected. Quantitative differences in the expression of "T" and tumor antigen species were reproducibly found.
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