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. 1970 Apr;65(4):1089-96.
doi: 10.1073/pnas.65.4.1089.

SV40-specific RNA in the nucleus and polyribosomes of transformed cells

U Lindberg, J E Darnell

SV40-specific RNA in the nucleus and polyribosomes of transformed cells

U Lindberg et al. Proc Natl Acad Sci U S A. 1970 Apr.

Abstract

Cells transformed by the oncogenic virus SV40 are known to contain viral DNA integrated into cellular DNA and to produce virus-specific RNA. It has been shown that nuclear molecules containing virus-specific sequences are considerably longer than presumed virus-specific mRNA molecules from cytoplasmic polyribosomes. This finding suggests the possibility that cytoplasmic mRNA is derived by the specific cleavage of larger nuclear RNA.

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