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Comparative Study
. 1970 Apr;45(240):196-7.
doi: 10.1136/adc.45.240.196.

Treatment of children with acute amoebic dysentery. Comparative trial of metronidazole against a combination of dehydroemetine, tetracycline, and diloxanide furoate

Comparative Study

Treatment of children with acute amoebic dysentery. Comparative trial of metronidazole against a combination of dehydroemetine, tetracycline, and diloxanide furoate

C J Rubidge et al. Arch Dis Child. 1970 Apr.

Abstract

Metronidazole cured 17 out of 20 children with acute amoebic dysentery. The 3 failures were later treated with dehydroemetine, tetracycline, and diloxanide furoate, but 2 required further courses of amoebicides before they were cured. A combination of dehydroemetine, tetracycline, and diloxanide furoate produced cure in 16 out of 19 children. The 3 failures were subsequently treated with metronidazole. 2 were cured; the remaining patient did not reattend for follow-up.

Metronidazole is as effective as the previously favoured combined regimen of amoebicides in children with amoebic dysentry. It is a safe and simple form of treatment.

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References

    1. Trans R Soc Trop Med Hyg. 1967;61(6):765-8 - PubMed
    1. Ann Trop Med Parasitol. 1967 Dec;61(4):511-4 - PubMed

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