doi: 10.1073/pnas.66.3.730.
Proteins specified by herpes simplex virus, IV. Site of glycosylation and accumulation of viral membrane proteins
- PMID: 4316680
- PMCID: PMC283111
- DOI: 10.1073/pnas.66.3.730
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Proteins specified by herpes simplex virus, IV. Site of glycosylation and accumulation of viral membrane proteins
Proc Natl Acad Sci U S A.
1970 Jul.
Abstract
The membrane glycoproteins specified by herpes simplex virus are synthesized concurrently with structural viral proteins and accumulate in the cytoplasm and in the membranes lining it. Analyses of free and membranebound polyribosomes, the cytoplasmic pool of soluble proteins, and purified smooth membranes showed that viral membrane proteins bind to membranes soon after synthesis and become glycosylated in situ.
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