doi: 10.1128/am.20.3.390-392.1970.
Viral aggregation resulting in the failure to correctly identify an unknown rhinovirus
- PMID: 4320921
- PMCID: PMC376945
- DOI: 10.1128/am.20.3.390-392.1970
Item in Clipboard
Viral aggregation resulting in the failure to correctly identify an unknown rhinovirus
Appl Microbiol.
1970 Sep.
Abstract
A seed lot of strain SF 1684 of rhinovirus type 2 prepared in human embryonic lung cells (WI-38) contained aggregates which interfered with its neutralization by homotypic or homologous antisera. The same virus showed no evidence of aggregation at five other passage levels studied. Virus in the seed lot was not identified correctly, and the titer of homologous antiserum was mistakenly considered to be low as a result of neutralization tests conducted with the aggregated virus. Filtration and a more easily effected treatment with sodium deoxycholate (1%) disaggregated the virus and restored its susceptibility to neutralization by homologous and homotypic antiserum.
Similar articles
-
Properties of rhinovirus plaque mutants.Proc Soc Exp Biol Med. 1970 Jul;134(3):677-82. doi: 10.3181/00379727-134-34859. Proc Soc Exp Biol Med. 1970. PMID: 4317259 No abstract available.
-
Detection of serotypic variants in viral preparations: sensitivity of a procedure for selection.J Virol Methods. 1989 Mar;23(3):333-8. doi: 10.1016/0166-0934(89)90165-1. J Virol Methods. 1989. PMID: 2541156
-
Antigenic variation of rhinovirus type 22.Proc Soc Exp Biol Med. 1970 Jan;133(1):329-33. doi: 10.3181/00379727-133-34468. Proc Soc Exp Biol Med. 1970. PMID: 4312716 No abstract available.
-
Isolation of rhinovirus from cattle in outbreaks of acute respiratory disease.Arch Gesamte Virusforsch. 1974;44(3):215-26. doi: 10.1007/BF01240609. Arch Gesamte Virusforsch. 1974. PMID: 4365603 No abstract available.
-
Viruses causing common respiratory infections in man.J Infect Dis. 1973 Mar;127(3):328-55. doi: 10.1093/infdis/127.3.328. J Infect Dis. 1973. PMID: 4348558 Review. No abstract available.
Cited by
-
Neutralization kinetics studies with type SAT2 foot-and-mouth disease virus strains. 1. Factors that influence the rate and pattern of neutralization.J Hyg (Lond). 1977 Feb;78(1):99-112. doi: 10.1017/s0022172400055984. J Hyg (Lond). 1977. PMID: 13123 Free PMC article.
-
An epidemic associated with echovirus type 18.J Hyg (Lond). 1972 Jun;70(2):325-34. doi: 10.1017/s0022172400022373. J Hyg (Lond). 1972. PMID: 4503872 Free PMC article.
-
Enterovirus type 71 infection in Melbourne.Bull World Health Organ. 1974;51(6):609-15. Bull World Health Organ. 1974. PMID: 4377551 Free PMC article.
-
Recovery of viruses from vegetable surfaces.Appl Environ Microbiol. 1982 Dec;44(6):1389-94. doi: 10.1128/aem.44.6.1389-1394.1982. Appl Environ Microbiol. 1982. PMID: 6297390 Free PMC article.
-
VP1 Amino Acid Residue 145 of Enterovirus 71 Is a Key Residue for Its Receptor Attachment and Resistance to Neutralizing Antibody during Cynomolgus Monkey Infection.J Virol. 2018 Jul 17;92(15):e00682-18. doi: 10.1128/JVI.00682-18. Print 2018 Aug 1. J Virol. 2018. PMID: 29848582 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
