Absence of interference during high-multiplicity infection by clonally purified vesicular stomatitis virus
- PMID: 4323713
- PMCID: PMC356132
- DOI: 10.1128/JVI.7.3.409-411.1971
Absence of interference during high-multiplicity infection by clonally purified vesicular stomatitis virus
Abstract
Stocks of vesicular stomatitis virus free of defective interfering particles were produced by serial clonal isolation. High-multiplicity infections with these stocks led to no interference or formation of defective interfering particles. Defective interfering particles were generated by three successive passages at high multiplicity.
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