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. 1971 Jul 2;173(3991):64-5.
doi: 10.1126/science.173.3991.64.

Angiotensin-forming enzyme in brain tissue

D Ganten, J L Minnich, P Granger, K Hayduk, H M Brecht, A Barbeau, R Boucher, J Genest

Angiotensin-forming enzyme in brain tissue

D Ganten et al. Science. .

Abstract

A renin-like enzyme is present in brain tissue and is independent of kidney and plasma renin. In the presence of homologous substrate it forms angiotensin. Administration of aldosterone significantly decreases this angiotensinforming enzyme activity, while administration of progesterone markedly enhances it.

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