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. 1979 May 4;204(4392):526-7.
doi: 10.1126/science.432659.

Human skin fibroblasts derived from papillary and reticular dermis: differences in growth potential in vitro

R A Harper, G Grove

Human skin fibroblasts derived from papillary and reticular dermis: differences in growth potential in vitro

R A Harper et al. Science. .

Abstract

Papillary fibroblasts, when compared to reticular fibroblasts from the same skin specimen, exhibit greater proliferative capacities in vitro. These results demonstrate a difference in function between morphologically similar cells obtained from the same tissue. Such findings represent an important consideration in the study of cell aging in vitro.

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