Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1971 Apr;122(2):219-24.
doi: 10.1042/bj1220219.

Accumulation of untranslated lactose-specific messenger ribonucleic acid during catabolite repression in Escherichia coli

M Aboud, M Burger

Accumulation of untranslated lactose-specific messenger ribonucleic acid during catabolite repression in Escherichia coli

M Aboud et al. Biochem J. 1971 Apr.

Abstract

When Escherichia coli K-12 Hfr.H was induced to synthesize beta-galactosidase in the presence of glucose, an untranslated lactose-specific mRNA (lac-mRNA), protected from decay, was found to accumulate progressively within the cells. The lac-mRNA accumulation was unaffected by the carbon source on which the cells had been grown before the induction. The amount of the lac-mRNA available for translation was affected by catabolite repression and 3':5'-cyclic AMP, but it remained unclear whether this was a direct effect on the formation of the lac-mRNA or a consequence of the effect on its translation.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. J Biol Chem. 1966 Oct 10;241(19):4434-43 - PubMed
    1. Proc Natl Acad Sci U S A. 1966 Nov;56(5):1599-605 - PubMed
    1. J Mol Biol. 1967 Mar 14;24(2):247-59 - PubMed
    1. Biochim Biophys Acta. 1967 Mar 29;138(1):107-23 - PubMed
    1. Science. 1967 Dec 1;158(3805):1186-8 - PubMed