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. 1972 Jan;69(1):86-8.
doi: 10.1073/pnas.69.1.86.

Growth inhibition of sympathetic cells by some adrenergic blocking agents (6-hydroxydopamine-mice and rats-immunosympathectomy-chemical sympathectomy-superior cervical ganglion)

P U Angeletti, R Levi-Montalcini

Growth inhibition of sympathetic cells by some adrenergic blocking agents (6-hydroxydopamine-mice and rats-immunosympathectomy-chemical sympathectomy-superior cervical ganglion)

P U Angeletti et al. Proc Natl Acad Sci U S A. 1972 Jan.

Abstract

Treatment of newborn mice and rats with the adrenergic blocking agents, guanethidine and bretylium tosylate, results in massive destruction of immature sympathetic nerve cells. A growth inhibition of the same cells is caused by reserpine. Similarities and differences between the effects elicited by these three ganglion blocking agents and a dopamine analog, 6-hydroxydopamine, are discussed.

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References

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