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. 1972 Feb 12;1(5797):409-11.
doi: 10.1136/bmj.1.5797.409.

Neuropathy associated with hepatitis in patients maintained on haemodialysis

A M Davison, I R Williams, C Mawdsley, J S Robson

Neuropathy associated with hepatitis in patients maintained on haemodialysis

A M Davison et al. Br Med J. .

Abstract

During a study of peripheral nerve function in chronic renal failure, 11 patients who were being treated by chronic intermittent haemodialysis developed serum hepatitis. Before the infection there was a trend towards improvement in nerve conduction velocities. A pronounced deterioration in the conduction velocities in motor fibres of peripheral nerves occurred in association with hepatitis. In the months after recovery from the infection there was again a trend towards improvement in conduction velocities. We suggest that this reflects the occurrence of a peripheral neuropathy which is at least in part demyelinating. The neuropathy is related to the serum hepatitis, but its pathogenesis is indeterminate.

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