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. 1972 Apr;23(4):675-8.
doi: 10.1128/am.23.4.675-678.1972.

Lack of significant oncogenicity of biological products in hamsters

C B Cox, J Landon, M G Valerio, A Palmer, R L Kirschstein, S H Singer

Lack of significant oncogenicity of biological products in hamsters

C B Cox et al. Appl Microbiol. 1972 Apr.

Abstract

A variety of biological products which included live and inactivated viral vaccines, inactivated rickettsial and bacterial vaccines, toxoids, and a multiple bacterial antigen product did not appear to be oncogenic for newborn hamsters following a single subcutaneous inoculation. The incidence of spontaneous tumors was approximately 4.7%, and this figure was not significantly altered by the inoculation of any of the test materials.

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