doi: 10.1126/science.176.4036.795.
Hepatic collagen metabolism: effect of alcohol consumption in rats and baboons
- PMID: 4337988
- DOI: 10.1126/science.176.4036.795
Item in Clipboard
Hepatic collagen metabolism: effect of alcohol consumption in rats and baboons
Science.
.
Abstract
Long-term ethanol feeding causes collagen accumulation in livers of rats and baboons. Activity of collagen proline hydroxylase in the liver is also stimulated, and incorporation of proline into collagen hydroxyproline in rat liver slices is significantly enhanced, a result indicating that increased synthesis is responsible, in part, for the collagen accumulation.
Similar articles
-
Influence of alcohol on collagen synthesis.Lancet. 1972 Mar 25;1(7752):697. doi: 10.1016/s0140-6736(72)90510-7. Lancet. 1972. PMID: 4125209 No abstract available.
-
Effect of chronic ethanol feeding on hepatic collagen in the monkey.Hepatology. 1983 Jan-Feb;3(1):41-4. doi: 10.1002/hep.1840030106. Hepatology. 1983. PMID: 6295907
-
Changes in hepatic collagen metabolism in rats produced by chronic ethanol feeding.Lab Invest. 1977 Feb;36(2):206-14. Lab Invest. 1977. PMID: 557149
-
Collagen accumulation can continue with decreased prolyl hydroxylase activity in the liver.Life Sci. 1985 Dec 16;37(24):2269-73. doi: 10.1016/0024-3205(85)90017-7. Life Sci. 1985. PMID: 2999546
-
Methods for analysis of connective-tissue macromolecules by determination of certain constituents.Methods Biochem Anal. 1977;24:39-91. doi: 10.1002/9780470110447.ch2. Methods Biochem Anal. 1977. PMID: 200826 Review. No abstract available.
Cited by
-
Collagen proline hydroxylase activity and 35S sulphate uptake in human liver biopsies.Gut. 1974 Apr;15(4):260-7. doi: 10.1136/gut.15.4.260. Gut. 1974. PMID: 4365510 Free PMC article.
-
Fatty liver: biochemical and clinical considerations.Am J Dig Dis. 1975 Dec;20(12):1142-70. doi: 10.1007/BF01070758. Am J Dig Dis. 1975. PMID: 1200009 No abstract available.
-
An increase of collagen biosynthesis in livers of rats submitted to chronic intoxication with ethanol.Mol Cell Biochem. 1989 Jan 23;85(1):43-8. doi: 10.1007/BF00223512. Mol Cell Biochem. 1989. PMID: 2725479
-
Ultrastructure of initial stages of perivenular fibrosis in alcohol-fed baboons.Am J Pathol. 1982 Feb;106(2):145-55. Am J Pathol. 1982. PMID: 7065113 Free PMC article.
-
Collagen metabolism in the liver. An annotated and supplemented report of a workshop at the National Institutes of Health on February 28 and March 1, 1977.Am J Dig Dis. 1978 Jul;23(7):641-59. Am J Dig Dis. 1978. PMID: 685930 No abstract available.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
